Dynamics of Brain Networks

Posted on March 25, 2013 by Tara Thiagarajan in Science. Comments Off on Dynamics of Brain Networks

My earlier academic work has focused on the dynamics of brain activity recorded using multielectrode arrays in various systems from organotypic slice cultures (2D brain networks in a dish) to electrodes implanted in awake monkeys and human patients undergoing surgical resection to treat epilepsy.  The most interesting discovery was of a phenomenon called ‘Coherence Potentials’, network level waveforms with complex temporal structures that traveled through the network without distortion. Recently we were able to relate these coherence potentials to simple motor behaviors in a human patient.


Tipping Points in the Brain (Scientific American India)  2010

Coherence potentials encode simple human sensorimotor behavior. Parameshwaran D, Crone NE, Thiagarajan TC.PLoS One. 2012;7(2):e30514.

Coherence potentials: loss-less, all-or-none network events in the cortex.Thiagarajan TC, Lebedev MA, Nicolelis MA, Plenz D.  PLoS Biol. 2010 Jan12;8(1)

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